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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3314dd156d1cff486a855e9cf16f545dccae06d58d4199f0a26dff49e6bbcf8a' 
  AND token = 'B8r8EGyQXu3vFQLLQHFuAxawGVD/DCH+r2ZKD8JSmak=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}