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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d373802344d2bc7beed43843d6e149a77df8c65275635015a4ff3ae23829307' 
  AND token = 'PVLF0qjtWqAMjNcwxg+CBx/PfPtz0fds1OrtQ7uMIYc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}