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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '721a736cfca3b187410a7869fb3bd8814c3e8a1d2b812bc809dd068f96d69cee' 
  AND token = '0RxGlF9Br0AaGbkvi4VP57f91zz/0xGC0xIAERYI33k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}