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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fe74ee0c673e493d1e2fdab1e1886afd658e33696a47d3feb034c039c9d73c4' 
  AND token = 'GuzJX1LcE1uHSl0aosyjR5WJ+YbjU6BvsUlcrGOdJx4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}