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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2aefd97b0e7ea876a8e473b63d2070616ecc26825907723d5be9118e97c75abd' 
  AND token = 'yTATVVlJrsf6XPKn1PX6UtoAEIqQW2NHCbwpCdSZjx8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}