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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a16bb5e7d93c2274a9411458c85deb5e050e230034db81a7379c9bcc0b40fdf7' 
  AND token = 'vze99tFXq8FcGd+Ag9D06G0wMMUt7lmsgzTE2gyfDOQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}