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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1814eed14fbee3a2299bac41a21a8379a3398bdad7c31d3a3554f94252eb63f2' 
  AND token = 'NPSE++D0dKaAcYxbZDIYcHtwLy4Lu6/PmzOA7WWv1KA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}