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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46e2b8fda7c3becf1e05692c57012c670eec7d0b71978fa849dfb52471f8d2ac' 
  AND token = 'tJPnldtwum4D3XNlsdvjSDnAFy0YTxxHv9N8tkBoUgk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}