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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2eb2298c779c627458b3468c43136c83dc97868ead219c8b09ade75869ab304' 
  AND token = '2dR05Ohz5+TUzCvsy3S+plpd9g4yUkUkKSfIw7za2Dc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}