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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd686b3e8cb02c8deb7b060887b8410e358885f83122465a37c77f8f4e994baa9' 
  AND token = 'I4Lfp9G9kzyvI/uXAdVfzl5I3to99XXKHkIrWfUV4g4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}