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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad0cfdd052ac98dbed23fbd4e9cfc25c60028653fefc805b840ad21eec968c96' 
  AND token = 'Vr9zMHb6NsuTfB+s4W+v+DB6ES3uPHSEWkrY6NtXrJE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}