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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dc45a77a47933a789e7b6796a0063ffef8f459f20df8b568b507b8113e1cfc80' 
  AND token = 'miE+6GS6T6E4i/vK/KKQ0+RQN5lnXTfs3WwKDf47zeY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}