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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e863299f64ea5471bd53ab5c77eabcaa877d882795e5284d4c2f90f7aa24919b' 
  AND token = 'x1vz6aPshweJr636LhrPCoTAjqe8tYblrq99AbTID+0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}