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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2242bc63faf6de72727e7a8917c9979b79015240b9697f1198c352b26f27a7d9' 
  AND token = 'fKbwAw8a1NJ1LGDZFKYLE4K3zifvWnL/ZSAimAkf7DQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}