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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4582aee87b98a81a8b6c61f7389b2540836eb5d7d40ea302f77423721b379714' 
  AND token = 'gEsUykI++A26fwcHX+5nlGnQyhQzJNbOnyQp5vRoriM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}