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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26cc5b7e37cdd3b71e58c1e07600f55a67c0a56bd8fda9908b39e3163038d799' 
  AND token = 'IEm2S8mgp/TxoFeP6k4iZ7j4eFD8W1xk8ejmsf51Pbg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}