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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ff199817128b74d301903392be4bcb06c35dc776efa83f47acadafb2aa9c0bf' 
  AND token = '3Mx2C/++43aYEon+mcUSFfdlnnX3T34HDeUGmK2kylM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}