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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e377d9f6b70ced06d6fd2f3a513c3ea04cda23df46fbdc047200f55638d8065e' 
  AND token = '4d7QhhuYCco+KeZkyJ+sJR2T20/htDzMTIMSZzGvW9s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}