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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '601e78ec33040a8fa43ce952dc40b919a3ce8d0e188a03e6f84968dbf6dcea04' 
  AND token = 's7DjxO4bP6J4IosDO4CCks3i48AN1N90b1fmuoyz+QI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}