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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c41e8a02a95c3bca0d3709367f7f6658897dc20e37b448178f69b9820c4e3fd5' 
  AND token = '+IL3VXKuRLSRCgFlWdbUN25LNNFUNSsl35jJp1eNimw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}