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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de0eaaf8de0f2e60ba0d6523a9271b121a2f065c72d6cfc329737276221e1a3c' 
  AND token = '0heGxlo4qZW/nHRDlWSr2Wrx4S+Ho4zmTZm6k5Ki+1w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}