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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '050e1fb346207e86db5969cd32c100d55f46e62510ade6eb33311b404ae5baf6' 
  AND token = 'ZqQmF3enZA+EIgXanIiemLFd6ZMY3VwB66tjLU8iSAI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}