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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd69e8202bd32f02548169d195b23dec5bf303ebbe50c60d2265fdc2558ed1239' 
  AND token = 'YqnL22QjKDFm5WCyM/XykNbRO76YTfYbi8GcQT8yZPY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}