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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0fe21601b744b8b720d1b17a990bddecde1062447205e4610e5b366a4bc8924a' 
  AND token = 'cymazXmNQUczKdI4EvfDXVPUdhiMM1mvUjKvYI/C2Hs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}