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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52ed79bba9d69f7e50b80c6d02191b0d4990069ed6d8fcbdbbbd2e0c2fb15c19' 
  AND token = 'vYfeEXrdMD4Az3xCNus8dIwbRxu8N5o+YN1Bc8L0uRc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}