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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1f2c78c87f2cf8477e1423afbf64ed342127781594e2b6e6e1056445e5bc7ef' 
  AND token = 'jXaD8JHrdDkRLEoFOnJPjZAJ0byIz2tH646agk1P7RU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}