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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b21e11df68fff3b51198ffd3a8f543d6252c2ec23d88a3be40ed2a33ea1311ee' 
  AND token = 'kJXFY2URpWCvKSq/pnL868KB94NMEf+FAeGA5n0oHas=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}