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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4de3802bf3f03195782f01e8a959de0bdae490bbfebfbf2584c778e17096cda' 
  AND token = 'pS+1UcbPWb6UoV/SrPF/9Fnly2t7UWi4tAVVm/viKEU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}