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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5154ed48ed1c5e17676909094cd1b09ade2cbe6b496f3d1c5e2a7b0356f0b01' 
  AND token = 'M+/yHqln/SXrqZGh/BbyR8nrjggGqgxpQD0084pRAtc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}