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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '23a787f7982ce9f1c79df625f3a8488b659ce644c3fe724c092feaf28db72819' 
  AND token = 'u660CbrP6aw+mKUqu9Wu08iG1VdyzdRv5RLtLrdXFKk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}