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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00fc4520606bb537eab6954d345ed244c51d711dcb902c8f536016664cd57c2e' 
  AND token = 'yE8WxzuUV5UGeiIrJUA0X7jllNIAXIYBM8jXbLUGH/Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}