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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49ea18e904614ab1e2dd0278f77da1e751046a04bea32b0c7b93c9c5246cd2f0' 
  AND token = 'KbtYlbgK6uZo6NHVOWVxVvHG0NoF/LF3fGPweMUP1uw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}