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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec6f83bf979e357817b31e2e32aaf3f56b3702429eda599ae770103b74f50013' 
  AND token = 'qV+oJ8AndurrUFq6zz5LLIb77FOKltsia3Yq4LngFdU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}