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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c1ecea66be6eeaf3e424e9b1c0198b6639ff2e316ce6d60f87c1f89afc10707' 
  AND token = 'x9vxhqLbqbZk9wBKjy3e9az23TKODLhO/DKto0mXFxc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}