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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b9a1a5b7d4e9631f04012c7e222c942ae8a066335380d5f3a79c228876cb6343' 
  AND token = 'b+o4bgExOS5kk0uSRkcTcz3c+0orDWoLYTccWWyjrUk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}