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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8538347423747c53e7f7b4601b4cbf1ec231b916877b5d2170a6b3c795d6439e' 
  AND token = 'lCoSVlhR0ZnH/zP8TQ5xsI41XVDcvrQBoxv36Gt/iQM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}