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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b7345fbd88f65ce9f6fab1fead9314c057567f1217de9ac9f082884b7f11a80' 
  AND token = 'Om0mpCKF5ToOh9GWX6HYZT1sLMEMy2CTA83lwi3Xj/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}