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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '437a3e7f71856de436b3c17adf03b54bfd00245abb38279fb2d21c8097acb06a' 
  AND token = 'uBa0Jfo8L5e5kSiXZVGB2CVi1t/s0a5aKrOVD0AQiHM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}