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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4dd26b7b94de9f7a9222e659bfbb367fb7cb199aa41f51e1db2a2a3639f430af' 
  AND token = 'DlJAcPaTcqclvNEO/9mhkzz3AyfZt9gE2cw/AaGiY+w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}