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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '412f0692cbec363d3fcb3bd09834e6a4204478fbd44d81d0d6874f97852118a4' 
  AND token = 'gz6znY/3PwZANf/qoSa8kTtMW4euCdPPPftGyWvDMl8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}