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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c43371df11ad9d49d7f53d19a6e6eb52877204fe5f24c6a28e83bfc012747da' 
  AND token = 'iWloXdOTNtzsFl7CVtFZO15xita0EzgvKatTg0x9+2c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}