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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2df860605a0e5e4c89967cd02ec36383659f862d0acd11d386cf5adee436f880' 
  AND token = 'ciSRY/TPz05QXAQ4HEX6LjTTH1T65Ceadl+sqn9Ogps=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}