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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e091b719f2bf6e7db7c1a15cbf8253afa7ed9bf4d731a3a3e5de200f414fba1d' 
  AND token = 'IQ2RTCRSxdal7aG2NsVsBEwcnd1EA+Vapj1ORSq+28Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}