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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1448a58914f39af412ddc2f5bc4e49b003067f0871e9c4e3948e9af818c95c45' 
  AND token = 'O0p8ystKPJFLQfVdtqXYrHOc5bQaWrdIspkqnkGSp9M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}