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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e461e5a648a668213cc5ca480094f3cf385d798945964e62496dc877835b80c' 
  AND token = '69sEb2wj2VeUbq84etFfTz1T95yxMBoHTPQC2F3Onww=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}