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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64f3f765235a3d4bf05dcdd3a43fcfbe45df4746853be58f67e0b2cb96e0a822' 
  AND token = 'bh5IxfEZKDZ2uZ2nCuRrT8MrZbiMCsN++0U0EOjy6uA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}