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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09fa2ae76fa54da8471d2f39b27199dea7124c7e5af230c7351116e2b86ec9c9' 
  AND token = 'PFMMDo/lSbi+naC02gnVb5uCVHsBz+ioCh4pIGcPrQA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}