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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43d6a0bdd9fd864919bcb1af0e44cb8e04582d3ad9dbf7a88e803769bbb7d049' 
  AND token = 'JvWSqbtNxfGQ8RsYqI/jro02xbuFfCIoKKWdklFyML8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}