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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22269863fffdabac636b9cd2274f51b3e3a166d35c6b822df68f28104deef228' 
  AND token = '81PKWB8oQ7aJ7bhOUGkRprSGc2C1ZVGrn5a34YiK80g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}