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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c41be826b260226c6212e8b3386ca7448891dd23f6e67d6cc87b01104f32db3e' 
  AND token = 'reqDzJsI2FUomQ+xfDwipKNR/1g23q57ZeO1G+FvG74=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}